Our Professional Team - HEAL Fertility

Dr. Jennifer MAK Sze Man

Specialist in Reproductive Medicine

Honorary Associate Professor of Practice in Reproductive Medicine, Department of Obstetrics and Gynaecology, Faculty of Medicine, CUHK

MB ChB (CUHK)

MRCOG

FHKCOG

FHKAM (Obstetrics and Gynaecology)

CERT RCOG (Reprod Med)

Chung JPW, Law TSM, Mak JSM, Liu RCY, Sahota DS, Li TC. Hyoscine butylbromide in pain reduction associated with ultrasound-guided manual vacuum aspiration: a randomized placebo-controlled trial. Reprod Biomed Online. 2022 Feb;44(2):295-303. doi: 10.1016/j.rbmo.2021.10.011. Epub 2021 Oct 25. PMID: 34949538.
Chung JPW, Law TSM, Mak JSM, Sahota DS, Li TC. Ovarian reserve and recurrence 1 year post-operatively after using haemostatic sealant and bipolar diathermy for haemostasis during laparoscopic ovarian cystectomy. Reprod Biomed Online. 2021 Aug;43(2):310-318. doi: 10.1016/j.rbmo.2021.05.003. Epub 2021 May 15. PMID: 34193356.
Alqawasmeh OA, Zhao M, Chan CP, Leung MB, Chow KC, Agarwal N, Mak JS, Wang CC, Pang CP, Li TC, Chu WK, Chan DY. Green tea extract as a cryoprotectant additive to preserve the motility and DNA integrity of human spermatozoa. Asian J Androl. 2021 Mar-Apr;23(2):150-156. doi: 10.4103/aja.aja_58_20. PMID: 33154201; PMCID: PMC7991818.
Mak JSM, Lao TT. Assisted reproduction in hepatitis carrier couples. Best Pract Res Clin Obstet Gynaecol. 2020 Oct;68:103-108. doi: 10.1016/j.bpobgyn.2020.02.013. Epub 2020 Mar 7. PMID: 32278628.
Saravelos SH, Balfoussia DT, Kong G, Chung J, Mak J, Chung C, Cheung LP, Li TC. Embryo migration following ART documented by 2D/3D ultrasound. Facts Views Vis Obgyn. 2020 Aug 5;12(2):143-148. PMID: 32832929; PMCID: PMC7431202.
Mak JSM, Lao TT, Leung MBW, Chung CHS, Chung JPW, Cheung LP, Li TC. Ovarian HBV replication following ovulation induction in female hepatitis B carriers undergoing IVF treatment: A prospective observational study. J Viral Hepat. 2020 Feb;27(2):110-117. doi: 10.1111/jvh.13210. Epub 2019 Oct 11. PMID: 31519044.
Chung J, Law T, Chung C, Mak J, Sahota DS, Li TC. Impact of haemostatic sealant versus electrocoagulation on ovarian reserve after laparoscopic ovarian cystectomy of ovarian endometriomas: a randomised controlled trial. BJOG. 2019 Sep;126(10):1267-1275. doi: 10.1111/1471-0528.15807. Epub 2019 May 23. PMID: 31038276.
Zhao M, Chan CPS, Cheung CWC, Alqawasmeh O, Wang RCC, Wu JCY, Lin ZX, Li TC, Chung JPW, Mak JSM, Law TSM, Chan DYL. A double-blinded, randomized placebo-controlled trial on the effect of traditional Chinese medicine formula Wuzi Yanzong pill on improving semen qualities in men with suboptimal parameters. Trials. 2019 Aug 29;20(1):540. doi: 10.1186/s13063-019-3647-2. PMID: 31464617; PMCID: PMC6716803.
Mak JSM, Leung MBW, Chung CHS, Chung JPW, Cheung LP, Lao TT, Li TC. Presence of Hepatitis B virus DNA in follicular fluid in female Hepatitis B carriers and outcome of IVF/ICSI treatment: A prospective observational study. Eur J Obstet Gynecol Reprod Biol. 2019 Aug;239:11-15. doi: 10.1016/j.ejogrb.2019.05.029. Epub 2019 May 24. PMID: 31158788.
Chung JPW, Chung CHS, Mak JSM, Li TC, Kong GWS. Efficacy, feasibility and patient acceptability of ultrasound-guided manual vacuum aspiration for treating early pregnancy loss. Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):71-76. doi: 10.1111/ajo.12811. Epub 2018 Apr 19. PMID: 29672838.
Kong GWS, Mak JSM, Li TC. Response: rLH versus uHCG supplementation in poor ovarian responders. Reprod Biomed Online. 2017 Oct;35(4):434. doi: 10.1016/j.rbmo.2017.05.022. Epub 2017 Aug 2. PMID: 28797742.
Mak JSM, Chung CHS, Chung JPW, Kong GWS, Saravelos SH, Cheung LP, Li TC. The effect of endometrial scratch on natural-cycle cryopreserved embryo transfer outcomes: a randomized controlled study. Reprod Biomed Online. 2017 Jul;35(1):28-36. doi: 10.1016/j.rbmo.2017.04.004. Epub 2017 Apr 19. PMID: 28476486.
Lao TT, Mak JSM, Li TC. Hepatitis B virus infection status and infertility causes in couples seeking fertility treatment-Indicator of impaired immune response? Am J Reprod Immunol. 2017 Apr;77(4). doi: 10.1111/aji.12636. Epub 2017 Jan 25. PMID: 28120470.
Saravelos SH, Kong GW, Chung JP, Mak JS, Chung CH, Cheung LP, Li TC. A prospective randomized controlled trial of 3D versus 2D ultrasound-guided embryo transfer in women undergoing ART treatment. Hum Reprod. 2016 Oct;31(10):2255-60. doi: 10.1093/humrep/dew206. Epub 2016 Sep 2. PMID: 27591231.

Infertility
Polycystic ovary syndrome
Endometriosis
Recurrent pregnancy loss
Repeated implantation failure
Early pregnancy assessment
Intrauterine insemination
In-vitro fertilization
Pre-implantation genetic testing
Reproductive surgery
Hysteroscopic surgery
Laparoscopic surgery
Emergency contraception
Contraception
Menopause
Adolescent gynaecology

Dr Sofie YUNG Shuk Fei

Specialist in Reproductive Medicine

Clinical Assistant Professor of Practice, Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, HKU

MB BS (HK)

MRCOG

FHKCOG

FHKAM (Obstetrics and Gynaecology)

Cert HKCOG (Reprod Med)

Infertility
Polycystic ovary syndrome
Endometriosis
Recurrent pregnancy loss
Repeated implantation failure
Early pregnancy assessment
Intrauterine insemination
In-vitro fertilization
Pre-implantation genetic testing
Reproductive surgery
Hysteroscopic surgery
Laparoscopic surgery
Emergency contraception
Contraception
Menopause
Sex therapy
Adolescent gynaecology

Dr. Mandy CHU Man Yee

Specialist in Gynaecologic Oncology

Honorary Clinical Associate Professor, Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, HKU

MB BS (HK)

FHKAM (Obstetrics and Gynaecology)

FHKCOG

Cert RCOG (Gynae Onc)

FRCOG

https://obsgyn.med.hku.hk/en/Staff/Dr-Mandy-MY-CHU-Profile

Lai THT, Lau LSK, Ngu SF, Chu MYM, Chan KKL, Ng EHY, Ngan HYS, Li RHW, Tse KY. Comparison of the multiples of the median of serum anti-müllerian hormone and pregnancy outcomes in patients with gestational trophoblastic disease: A case-control study. Cancer Med. 2024 Apr;13(7):e7134.
Chan KKL, Liu SS, Lau LSK, Ngu SF, Chu MMY, Tse KY, Cheung ANY, Ngan HYS. PAX1/SOX1 DNA Methylation Versus Cytology and HPV16/18 Genotyping for the Triage of High-Risk HPV-Positive Women in Cervical Cancer Screening: Retrospective Analysis of Archival Samples. BJOG. 2024 Sep 26. doi: 10.1111/1471-0528.17965. Epub ahead of print. PMID: 39327707.
Lee EYP, Ip PPC, Tse KY, Chiu KWH, Chu MMY, Chai YK, Wu PY, Law JYP, Kwok ST, Chiu WK, Ngan HYS. Prospective validation of the role of PET/CT in detecting disease after neoadjuvant chemotherapy in advanced ovarian cancer. Eur Radiol. 2024 Mar 9. doi: 10.1007/s00330-024-10674-y. Epub ahead of print. PMID: 38460014.
Lai THT, Lau LSK, Ngu SF, Chu MYM, Chan KKL, Ng EHY, Ngan HYS, Li RHW, Tse KY. Comparison of the multiples of the median of serum anti-müllerian hormone and pregnancy outcomes in patients with gestational trophoblastic disease: A case-control study. Cancer Med. 2024 Apr;13(7):e7134. doi: 10.1002/cam4.7134. PMID: 38545760; PMCID: PMC10973878.
Leung TW, Damodaran P, Torres R, Chuncharunee S, Chu MY, Gamilla Z, Lim NR, Luna J, Huang JP, Li WH, Tran TN, Sathar J, Jaisamrarn U. Expert consensus on improving iron deficiency anemia management in obstetrics and gynecology in Asia. Int J Gynaecol Obstet. 2023 Apr 24. doi: 10.1002/ijgo.14804. Epub ahead of print. PMID: 37096333.
Kwok ST, Chan KKL, Tse KY, et al. Outcome after loop electrosurgical excision procedure for cervical high-grade squamous intraepithelial lesion. Taiwan J Obstet Gynecol. 2023;62(1):45-49. doi:10.1016/j.tjog.2022.10.004
Luk, H.M.; Ngu, S.F.; Lau, L.S.K.; Tse, K.Y.; Chu, M.M.Y.; Kwok, S.T.; Ngan, H.Y.S.; Chan, K.K.L. Patient-Initiated Follow-Up in Ovarian Cancer. Curr. Oncol. 2023, 30, 3627-3636. https://doi.org/10.3390/curroncol30040276
Chu MM, Cheung CS, Ngu SF, Tse KY, Ip PP, Cheung AN, Ngan HY, Chan KK. The Value of Four-Quadrant Cervical Biopsy in Women with Different Colposcopic Impressions. Diagnostics (Basel). 2023 Jul 16;13(14):2384. doi: 10.3390/diagnostics13142384. PMID: 37510128; PMCID: PMC10378482.
Ngu S.F., Chai Y.K.V., Choi K.M.C., Leung T.W., Li J., Kwok S.T.G., Chu M.Y.M., Tse K.Y., Cheung V.Y.T., Ngan H.Y.S. and Chan K.K.L., Diagnostic Performance of Risk of Malignancy Algorithm (ROMA), Risk of Malignancy Index (RMI) and Expert Ultrasound Assessment in a Pelvic Mass Classified as Inconclusive by International Ovarian Tumour Analysis (IOTA) Simple Rules., Cancers (Basel). . 2022, 14(3), 810.
Chan K.K.L., Chai Y.K.V., Cheung V.Y.T., Choi K.M.C., Chu M.Y.M., Siu K.Y., Tse K.Y. and Ngan H.Y.S., Use of ultrasonographic rules and tumour marker HE4 level to predict malignancy of a pelvic mass: abridged secondary publication, Hong Kong Med J. 2022
Ngu S.F., Tse K.Y., Chu M.Y.M., Ngan H.Y.S. and Chan K.K.L., Olaparib dose re-escalation in ovarian cancer patients who experienced severe and/or uncommon adverse events: A case series., Asia Pac J Clin Oncol.. 2021, 17, 3-11. http://dx.doi.org/10.1111/ajco.13584
Chan K.K.L., Liu S., Wei N., Ngu S.F., Chu M.Y.M., Tse K.Y., Lau S.K., Cheung A.N.Y. and Ngan H.Y.S., Primary HPV testing with cytology versus cytology alone in cervical screening—A prospective randomized controlled trial with two rounds of screening in a Chinese population , International Journal of Cancer. 2020. http://dx.doi.org/10.1002/ijc.32861
Liu S., Chan K.K.L., Chu K.H., Wei N., Lau S.K., Ngu S.F., Chu M.Y.M., Tse K.Y., Ip P.C.P., Ng E.K.O., Cheung A.N.Y. and Ngan H.Y.S., Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer, 2018. http://dx.doi.org/10.1002/1878-0261.12383(Publication No. : 294143)
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69. http://dx.doi.org/10.12892/ejgo3763.2018 (Publication No. : 284270)
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018. http://dx.doi.org/10.1093/ajcp/aqy039 (Publication No. : 285802)
Ngu SF, Chu MM, Ip PP, Ngan HY. Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? J Obstet Gynaecol Can. 2017 Mar 30. S1701-2163(16)39741-9.
Ngu SF, Wei N, Kwan TT, Chu MM, Tse KY, Chan KK, Ngan HY. Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial. J Psychosom Obstet Gynaecol. 2017 Apr 10:1-10.
SF Ngu, N Wei, TTC Kwan, MMY Chu, KY Tse, KKL Chan, HYS Ngan. Impact of different educational interventions on psychosocial wellbeing of Hong Kong Chinese women with a positive high-risk human papillomavirus and normal cervical cytology. Journal of Psychosomatic Obstetrics & Gynecology 2017: 10: 1 – 10.
Chu MM, Tse KY, Chan KK, Cheung AN, Ngan HY. Placental site trophoblastic tumour – a distinct entity of gestational trophoblastic disease: experience from a tertiary referral center in Hong Kong. J Reprod Med. 2016 Aug;61(4):351-6
Chu MM, Ma Y, Tse KY, Chan KK, Ngan HY. Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia. International Journal of Gynecological Cancer 2015 Mar;25(3):498-503.
Chu MYM, Liu S, Tam KF, Ip PCP, Cheung ANY and Ngan HYS. The Significance of Mismatch Repair Deficiency in Young Patients With Endometrial Cancer. Int J Gynecol Pathology 2015, 34: 403-410.
Leung TW, Liu S, Leung CY, Chu MM, Cheung ANY and Ngan HYS. HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis. J Med Virol 2015, 2015 Jun;87(6):1022-33.
Lee EY, Yu X, Chu MM, Ngan HY, Siu SW, Soong IS, Chan Q, Khong PL. Perfusion and diffusion characteristics of cervical cancer based on intraxovel incoherent motion MR imaging-a pilot study. Eur Radiol. 2014 Jul;24(7):1506-13
Lee EY, Khong PL, Tse KY, Chan KK, Chu MM, Ngan HY. Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. Nucl Med Commun. 2013; 34(12):1185-9.
Chu MM, Lee WC, Leung JL, Wong V. Modified symbolic play test for Oriental children. Pediatr Int. 2006; 48(6):519-24.
Au YL, Ma KM, Sy WM, Lee WC, Leung LS, Au Yeung YC, Chu MY, Chung CK, Ho PK, Lau WL, Law PK, Siu PY, Tse KS, Wong V. Brain Dev. Use of developmental language scales in Chinese children. 2004; 26(2):127-9.

Surgery for benign and malignant gynaecological conditions, including hysteroscopy, laparoscopy, robotic-assisted operation and laparotomy
Uterine cancer
Ovarian cancer / borderline ovarian tumour
Cervical cancer
Vaginal and vulval cancer
Cervical screening – Pap smear and HPV tests
Colposcopy-related procedure for pre-malignant condition (intra-epithelial neoplasia) of the lower female genital tract
Ovarian cyst
Endometriosis
Fibroid and Adenomyosis
Dysmenorrhea
Abnormal menstrual cycle & uterine bleeding
Contraception
Menopause
HPV vaccine

Dr. Vicky LEE Yun Ting

Specialist in Obstetrics & Gynaecology

MB ChB (CUHK)

MRCOG (UK)

FHKCOG

FHKAM (O&G)

Gynaecology services include:

Gynecological surgery, including laparoscopic/minimally invasive surgery, laparotomy, and hysteroscopic surgery
Surgical management of endometriosis, ovarian cysts and fibroids
Hysterectomy
Colposcopy and related procedures
Preventative women’s care, including Pap smears (cervical screening), HPV tests, and HPV vaccine
Gynecological ultrasound
Contraception management
Menstrual dysfunction: evaluation and treatment
Polycystic ovarian syndrome (PCOS): diagnosis and management
Pelvic pain and endometriosis care
Subfertility diagnosis and investigation
Female genitourinary system dysfunction, including urinary incontinence and pelvic organ prolapse: diagnosis and management
Menopausal health management

Obstetrics services include:

Pre-pregnancy assessment and counseling-Early pregnancy assessment and management (miscarriage/ectopic pregnancy)
Pregnancy and postnatal care
Obstetrical ultrasound
Vaginal delivery and caesarean section

PhD Michelle LAW Pui Man

Registered Chinese Medicine Practitioner (HK)

Adjunct Assistant Professor, Centre for Health Education and Health Promotion, School of Public Health, CUHK

BChiMed (CUHK)

PhD in Public Health (Family Medicine) (CUHK)

Law MPM, Chuh AAT, Lee A, Molinari N. Acne prevalence and beyond – acne disability and its predictive factors amongst the late Chinese adolescents in Hong Kong. Clinical and Experimental Dermatology 2010; 35(1); 16-21.
Law MPM, Chuh AAT, Molinari N, Lee A. An Investigation of the Association Between Diet and Occurence of Acne: A Rational Approach from Traditional Chinese Medicine Perspective. Clinical and Expertimental Dermatology 2010; 35(1); 31-35.
Law MPM, Chuh AAT, Lee A. Validation of Cantonese Cardiff Acne Disability Index. Hong Kong Medical Journal 2009; 15:12-7.
Law MPM, Chuh AAT, Lee A. Acne: its psychological consequences and management. Hong Kong Practitioner 2006; 28: 1-5.
Chung V, Law MPM, Wong S, Mercer S, Grifiths S. Development Postgraduate Education for Chinese Medicine Practitioners: A Hong Kong. BMC Medical Education 2009; 9:10.
Law MPM, Chuh A. A synopsis of acne vulgaris and its variants (in Chinese). Next Publications Ltd., Next Media Group, 2007 (ISBN 9789625778631)
The dietary modification for patients with acne – from a Chinese Medicine perspective (Interview). Health Plus Magazine 2009; 108: 6-9
Lee A, Law MPM, Chuh AAT. Common adolescent health problems would cause psychological disability – acne as an example. 36th Annual Scientific Meeting of the Society for Academic Primary Care. July 2007, London.
Law MPM, Chuh AAT, Lee A, Molinari N. A clinical study investigating the unjustified association of diet and acne: a rational approach form traditional Chinese medicine perspective. International Congress on Complementary Medicine Research 2007. May 2007, Munich. Hosted by Centre for Complementary Medicine Research, Technical University of Munich in cooperation with the International Society for Complementary Medicine Research.
Law MPM, Chuh AAT, Lee A, Molinari N. A more personalised approach: A randomised control trial on the effectiveness of traditional-Chinese-medicine-syndrome-tailored dietary advice for patients with acne. International Congress on Complementary Medicine Research 2010. May 2010, Tromso. Hosted by Centre for Complementary Medicine Research, National Research Centre in Alternative and Complementary Medicine of the University of Tromso in cooperation with the International Society for Complementary Medicine Research.

Professor CHAN Yiu Leung David

External Consultant

Assistant Professor, Department of Obstetrics and Gynaecology, CU

DPhil (Oxon)

MPhil (CUHK)

BSc (Ulster)

Senior Clinical Embryologist (ESHRE)

Certified Medical Laboratory Scientist (ASCP)

Jacki WONG Yuk Ying

Deputy Laboratory Director

Level II Certificate of Clinical Embryologist, HKACE

Part I Registration in Medical Laboratory Technologists Board HK

Diploma in Medical Laboratory Science, HKPU

National Diploma in Science, BTEC

Associate of the Institute of Biomedical Science, IBMS

Bachelor of Applied Science (MLS), CSU Australia

Postgraduate Award in Assisted Reproduction Technology, Warwick UK

A retrospective analysis of artificial oocyte activation in patients with low or no fertilisation in intracytoplasmic sperm injection cycles, Journal of Obstetrics and Gynaecology, DOI: 10.1080/01443615.2021.1922878
Hyaluronic acid-enriched transfer medium for frozen embryo transfer: a randomized, double-blind, controlled trial. Fertility and Sterility 2021 Apr 9;S0015-0282(21)00133-3
HUMREP-20-0374, Co-author in on-line manuscript submission Title: Hyaluronic acid-enriched transfer medium for frozen-thawed embryo transfer: a randomized double-blind controlled trial." Human Reproduction 25/3/2020
First author, Poster presentation of an abstract “Laboratory strategy to poor fertilization after ICSI” in the 9th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE)—Cutting Edge of Reproductive Medicine, 2/5/2019 to 5/5/2019, held in HKECC, HKSAR, CHINA
First author, Poster presentation of an abstract “ A retrospective comparison of pregnancy outcomes following the first embryo transfer in stimulated or frozen-thawed cycles” in the 9th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE)—Cutting Edge of Reproductive Medicine, 2/5/2019 to 5/5/2019, held in HKECC, HKSAR, CHINA
First author, A Poster presentation of an abstract “Failed Fertilization—is ICSI an ultimate solution?” at the 8th Conference of the Pacific Rim Society of Fertility and Sterility, 27-29 May 2011 in Hong Kong Convention Centre, Hong Kong SAR.
Collaborated author, A Cross-sectional Study of the relationship of serum Folic acid, vitamin B12, zinc and magnesium with semen parameters in infertile couples in Hong Kong, Hong Kong Journal of Gynaecology Obstetrics and Midwifery, P. 173-186, 2015;15(2)
Travel Expense Award First author-“ Laboratory strategy for Idiopathic Infertility” presented at the 4th Conference of the Pacific Rim Society for Fertility and Sterility, 8-11 March 2004 in Okinawa Japan
First author “Phasing-in of Vitrification into routine practice—why, how and what”, Hong Kong Medical Journal P. 119-126 Vol 17 No. 2 April 2011
Poster presentation of an abstract “Clinical results of the In Vitro Fertilization (IVF) program at Kwong Wah Hospital”, Wong AYK, Wong JYY, Luk KL, Yeo ELK, Chan KL, Tang LCH, at the2nd Workshop on ART ----24-28 Nov 1999---University of Hong Kong
Screening of human immuno-deficiency virus infection in pregnant women. Tse HY, Lai FK, Wong J, Chan A, Tang LCH. HONG KONG MEDICAL JOURNAL 2000
First author, Poster presentation of an abstract “Silane–coated colloidal silica is better than Percoll in the recovery of progressive motile sperms” at the 2nd Workshop on ART ----24-28 Nov 1999---University of Hong Kong